Cover Feature: Flavin‐Dependent Monooxygenases NotI and NotI′ Mediate Spiro‐Oxindole Formation in Biosynthesis of the Notoamides (ChemBioChem 17/2020)
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چکیده
منابع مشابه
NotI subtraction and NotI-specific microarrays to detect copy number and methylation changes in whole genomes.
Methylation, deletions, and amplifications of cancer genes constitute important mechanisms in carcinogenesis. For genome-wide analysis of these changes, we propose the use of NotI clone microarrays and genomic subtraction, because NotI recognition sites are closely associated with CpG islands and genes. We show here that the CODE (Cloning Of DEleted sequences) genomic subtraction procedure can ...
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ژورنال
عنوان ژورنال: ChemBioChem
سال: 2020
ISSN: 1439-4227,1439-7633
DOI: 10.1002/cbic.202000548